Herpes simplex type I subunit vaccine
AssigneeMerck & Co., Inc.
InventorsAlexander U. Bertland, George P. Lampson
Life of this patent
Estimating the term…
Abstract
A herpes simplex type I subunit vaccine is prepared from infected chick embryo cells by ultra extraction of the virus while the infected cells are still attached to the growth surface.
Claims1
A herpes simplex type I immunogenic antigen having a molecular weight greater than 1.times.10.sup.6 daltons and comprising about 5 or 6 bands having minimum molecular weight greater than 68,000 daltons, the antigen being substantially free of glycoprotein and of DNA, and containing from about 0.1 to about 0.7 .mu.g carbohydrate per 1 .mu.g of protein and containing one lipid band having a molecular weight between about 60,000 and about 70,000 daltons.
Dependencies are inferred from the claim text.