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US 4,540,565 AGranted
Reduced IgG in low ionic strength medium for immunohematologic agglutination
AssigneeAmerican Hospital Supply Corporation
InventorsDaniel P. Roman, Jr., Mitchell J. Fruitstone
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Abstract
An antiserum for immunohematologic agglutination reactions involving IgG antibodies wherein reduced IgG antibodies are suspended in a low ionic strength medium.
Claims29
An antiserum for immunohematologic agglutination reactions comprising an erythrocyte-agglutinating amount of a chemically reduced IgG antibody dissolved in a low ionic strength medium containing sufficient salt of an alkali or alkaline earth metal to provide an ionic strength equivalent to about a 0.01 molar to about a 0.10 molar solution of sodium chloride;
- sufficient organic solute to provide an osmolality of from about 150 mOsm per kg. H.sub.2 O, to about 450 mOsm per kg. H.sub.2 O and a pH of from about 6.0 to about 8.0.
Dependencies are inferred from the claim text.