Antibiotics X-14889 A, C and D
AssigneeHoffmann-La Roche Inc.
InventorsChao-Min Liu, John Westley
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Abstract
There is presented antibiotic compounds designated as Antibiotics X-14889 A, C and D of the formulas ##STR1## wherein (for X-14889A) R.sub.1 is methyl, R.sub.2 is methyl, R.sub.3 is hydrogen, R.sub.4 is methyl and R.sub.5 is hydrogen or (for X-14889C) R.sub.1 is hydrogen, R.sub.2 is methyl, R.sub.3 is hydrogen, R.sub.4 is methyl and R.sub.5 is CO.sub.2 H or ##STR2## and the pharmaceutically acceptable salts thereof. The compounds exhibit antimicrobial activity and one of the compounds X-14889C also exhibits activity against Treponema hyodysenteriae (in vitro), Plasmodium berghei and as food efficiency enhancers in ruminants. Also presented is a process to produce the above compounds and another known component Antibiotic X-14889B.
Claims3
A compound of the formula ##STR5## and the pharmaceutically acceptable salts thereof.
A compound of the formula ##STR6## and the pharmaceutically acceptable salts thereof.
A compound of the formula ##STR7## and the pharmaceutically acceptable salts thereof.
Dependencies are inferred from the claim text.