Pharmaceutical formulation
AssigneeBeecham Group Limited
InventorsDavid J. Rooke, Barry W. Burnstead
Life of this patent
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Abstract
A unit dose pharmaceutical composition suitable for oral administration which composition comprises a pharmaceutically acceptable carrier, a desiccant, amoxycillin trihydrate equivalent to 20 mg to 1500 mg of amoxycillin and potassium clavulanate equivalent to 20 mg to 500 mg of clavulanic acid, with the proviso that the weight ratio of amoxycillin to clavulanic acid is in the range 12:1 to 1:1; characterized in that the composition is in tablet form, wherein the desiccant is edible and incorporated within the tablets.
Claims12
A pharmaceutical composition in unit does tablet form suitable for oral administration to humans and animals which comprises amoxycillin trihydrate equivalent to 20 mg to 1500 mg of amoxycillin, potassium clavulanate equivalent to 20 mg to 500 mg of clavulanic acid, the weight ratio of amoxycillin to clavulanic acid being in the range of from 12:1 to 1:1, an effective amount of a colloidal silica having an average particle size of 8 .mu.m and a BET specific surface area of about 750 m.sup.2 /g incorporated within each tablet as a desiccant, and a pharmaceutically acceptable carrier suitable for tablets.
Dependencies are inferred from the claim text.