A47934 Antibiotic and process for production thereof
AssigneeEli Lilly and Company
InventorsRobert L. Hamill, Ralph E. Kastner
Life of this patent
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Abstract
Antibiotic A47934 is produced by submerged, aerobic fermentation of new Streptomyces toyocaensis NRRL 15009. The antibiotic is active against gram-positive bacteria in vitro and in vivo. It promotes growth in poultry and swine and serves to enhance feed efficiency in ruminant animals having a developed rumen.
Claims10
A method of increasing the efficiency of feed utilization by ruminant animals having a developed rumen function which comprises the oral administration to such animals of a propionate-increasing amount of antibiotic A47934, or a pharamaceutically-acceptable, non-toxic salt thereof.
A feed composition useful for increasing the efficiency of feed utilization by ruminant animals having a developed rumen which comprises a propionate-increasing amount of antibiotic A47934, or a pharmaceutically-acceptable, non-toxic salt thereof, and a standard feed ration.
A method for promoting growth in chickens which comprises the oral administration to said chickens of a growth-promoting amount of antibiotic A47934, or a pharmaceutically-acceptable, non-toxic salt thereof.
A method for promoting the growth of weanling pigs which comprises the oral administration of a growth-promoting amount of antibiotic A47934, or a pharmaceutically-acceptable, non-toxic salt thereof.
A feed composition useful for promoting the growth of chickens which comprises a standard chicken feed ration and an effective amount of antibiotic A47934 or a pharmaceutically-acceptable, non-toxic salt thereof.
A feed composition useful for promoting the growth of weanling pigs which comprises a standard feed ration and an effective amount of antibiotic 47934 or a pharmaceutically-acceptable, non-toxic salt thereof.
A method for treating bacterial infections in a mammal which comprises administering a therapeutically-effective dose of antibiotic A47934 or a pharmaceutically-acceptable, non-toxic salt thereof.
A pharmaceutical composition suitable for the treatment of infections in a mammal caused by gram-positive bacteria which comprises antibiotic A47934 or a pharmaceutically-acceptable, non-toxic salt thereof and a pharmaceutically-acceptable carrier or diluent.
Dependencies are inferred from the claim text.