Methods for disinfecting and preserving contact lenses
AssigneeBausch & Lomb Incorporated
InventorsLai Ogunbiyi, Francis L. Scott, Francis X. Smith
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AssigneeBausch & Lomb Incorporated
InventorsLai Ogunbiyi, Francis L. Scott, Francis X. Smith
Estimating the term…
Improved methods of disinfecting and/or preserving contact lenses comprises treating said lenses with an effective concentration of a solution comprising a biguanide or a water soluble salt of the formula: ##STR1## wherein R.sub.1 and R.sub.3 are selected hydrogen, halogen, alkyl, alkoxy, nitro, --SO.sub.2 R.sub.4, carboxyl or hydroxyl where R.sub.4 is --NH.sub.2, --NHR', --NR'R", --OR' or --O--aryl in which R' and R" are alkyl or alkoxy; R.sub.2 is hydrogen or halogen and X is hydrogen or alkyl, provided that when R.sub.2 is halogen then both R.sub.1 and R.sub.3 are hydrogen and X is alkyl. The method provides for disinfecting and/or preserving contact lenses wherein the monomeric biguanide-containing solutions offer a wide spectrum of antimicrobial activity with nominal binding and concentrating onto lens surfaces and low levels of eye tissue irritation or inflammation.
A method of disinfecting and/or preserving contact lenses which comprises treating said lenses with an antimicrobial amount of a solution comprising a biguanide or its water soluble salt of the formula:
A method of disinfecting and/or preserving contact lenses which comprises treating said lenses with an effective amount of a solution comprising a microbicidally effective mixture of a biguanide and at least one other germicidal agent, said biguanide having the formula:
The method of caim 14 wherein R.sub.2 is chlorine and X is lower alkyl.
Dependencies are inferred from the claim text.