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US 4,536,578 AGranted
1-[3-(6-Fluoro-1,2-benzisoxazol-3-yl)propyl]-4-(substituted)piperazines
AssigneeHoechst-Roussel Pharmaceuticals Inc.
InventorsLarry Davis, Joseph T. Klein
Life of this patent
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Abstract
Novel 1-[3-(6-fluoro-1,2-benzisoxazol-3-yl)propyl]-4-(substituted)piperazines, processes for the preparation thereof, and methods of treating psychoses, alleviating pain, and reducing blood pressure, employing compounds and compositions thereof are disclosed.
Claims19
A compound of the formula ##STR7## wherein R is loweralkyl, benzyl, 2-hydroxyethyl, pyridyl or a group of the formula ##STR8## wherein R.sub.1 is hydrogen, loweralkyl, loweralkoxy, halogen or trifluoromethyl;
- the optical antipodes thereof;
- or pharmaceutically acceptable acid addition salts thereof.
Dependencies are inferred from the claim text.