Hydrophilic polymers and contact lenses made therefrom
AssigneeBarnes-Hind, Inc.
InventorsDrahoslav Lim, Chidambar L. Kulkarni, Dennis A. Repella
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Abstract
An interpenetrating network polymer is obtained by mixing hydrophilic monomer vinyl pyrrolidone and hydrophobic monomer (5-alkylene-m-dioxanyl) acrylic ester in the presence of at least two crosslinking agents and, optionally, hydroxyalkyl acrylic ester and catalysts and causing polymerization to occur. Contact lenses made from the polymer have high tensile strength and can absorb a high degree of water.
Claims6
A contact lens comprised of an interpenetrating network polymer comprising
- (a) hydrophilic vinyl pyrrolidone, 50-80% by weight;
- (b) a first crosslinking agent having an affinity for hydrophilic vinyl pyrrolidone, 0.1-1.0% by weight;
- said first crosslinking agent being 3,3'-ethylidine-bis (N-vinyl-2-pyrrolidone), diallyl itaconate, diallyl maleate, diallyl fumarate, dimethallyl fumarate, dimethallyl maleate, diallyl diglycollate, diethylene glycol bis (allyl carbonate), diallyl oxalate, diallyl adipate, diallyl succinate, diallyl azelate, divinyl benzene, divinyl adipate, or divinylethers;
- (c) (5-alkylene-m-dioxanyl)acrylic ester, 10-45% by weight, having the formula ##STR2## wherein R and R.sub.1 are independently H or C.sub.1 -C.sub.4 alkyl,
- R.sub.2 and R.sub.3 are independently H, C.sub.1 -C.sub.4 alkyl, or phenyl, and
- n is an integer from 1-4;
- (d) hydroxyalkyl acrylic ester, 0-20% by weight;
- (e) a second crosslinking agent having an affinity for acrylic esters of (c) and (d), 0.1-2% by weight, said agent being neopentyl glycol dimethacrylate, ethylene glycol dimethacrylate, polyethylene glycol dimethacrylate, 1,6-hexane diol dimethacrylate, glycerol trimethacrylate, pentaerythritol trimethacrylate, pentaerythritol tetramethacrylate, trimethylol propane trimethyacrylate, allylmethacrylate, or corresponding acrylates.
A contact lens comprised of an interpenetrating network polymer comprising
- (a) N-vinyl-2-pyrrolidone, 50-65%;
- (b) 3,3'-ethylene-bis (N-vinyl-2-pyrrolidine), 0.3-0.5%;
- (c) (5-methyl-5-m-dioxanyl)methyl methacylate, 30-33%;
- (d) 2-hydroxyethyl methacrylate, 5-8%;
- and
- (e) neopentyl glycol dimethacrylate 0.1-2.0%;
- wherein the percentages are by weight based on the total weight of monomer exclusive of crosslinking agents.
A contact lens comprised of an interpenetrating network polymer comprised of 50-80% of a first network comprised of N-vinyl-2-pyrrolidone crosslinked with 0.1-1.0% by weight, 3,3'-ethylidene-bis (N-vinyl-2-pyrrolidone), diallyl itaconate, diallyl maleate, diallyl fumarate, dimethallyl fumarate, dimethallyl maleate, diallyl diglycollate, diethylene glycol bis (allyl carbonate), diallyl oxalate, diallyl adipate, diallyl succinate, diallyl azelate, divinyl benzene, divinyl adipate, or divinylethers, and the balance a second network comprised of 2-hydroxyethyl methacrylate, 0-20% by weight and (5-methyl-5-m-dioxanyl)methyl methacrylate, 10-45% by weight, crosslinked with 0.1-2% neopentyl glycol dimethacrylate, ethylene glycol dimethacrylate, polyethylene glycol dimethacrylate, 1,6-hexane diol dimethacrylate, glycerol trimethacrylate, pentaerythritol trimethacrylate, pentaerythritol tetramethacrylate, trimethylol propane trimethyacrylate, allylmethacrylate, or corresponding acrylates;
- wherein the percentages are by weight based on the total weight of monomer exclusive of crosslinking agents.
Dependencies are inferred from the claim text.