7-Oxabicycloheptane substituted prostaglandin interphenylene analogs useful in the treatment of thrombolytic disease

A compound having the structural formula ##STR39## and including all stereoisomers thereof;

• wherein m is 1 to 4;
• n is 1 to 8;
• p is 1 to 4;
• R is H, lower alkyl or alkali metal;
• and R.sup.1 is lower alkyl, aryl, aralkyl, cycloalkyl, cycloalkylalkyl or lower alkenyl, wherein the term lower alkyl or alkyl by itself or as part of another group contains 1 to 12 carbons and is unsubstituted or substituted with halo, trifluoromethyl, alkoxy, aryl, alkyl-aryl, haloaryl, cycloalkyl or alkylcycloalkyl;
• the term aryl by itself or as part of another group contains 6 to 10 carbons and is unsubstituted or substituted with 1 or 2 lower alkyl groups 1 or 2 halogen groups and/or 1 or 2 lower alkoxy groups;
• the term cycloalkyl by itself or as part of another group contains 3 to 12 carbons and is unsubstituted or substituted with 1 or 2 halogens, 1 or 2 lower alkyl groups and/or 1 or 2 lower alkoxy groups;
• the term lower alkenyl by itself or as part of another group contains 2 to 12 carbons;
• the terms (CH.sub.2).sub.m and (CH.sub.2).sub.p include 1 to 4 carbons in the normal chain and the term (CH.sub.2).sub.n includes 1 to 8 carbons in the normal chain;
• and the terms (CH.sub.2).sub.m (CH.sub.2).sub.n and (CH.sub.2).sub.p may be unsubstituted or include one or more lower alkyl substituents.