Certain N-(pyridyl) indoles

A compound of the formula ##STR16## wherein Ar is 3- or 4-pyridyl or 3- or 4-pyridyl substituted by lower alkyl;

• R.sub.1 is hydrogen, halogen, trifluoromethyl, lower alkyl, hydroxy, acylated or etherified hydroxy, lower alkyl-(thio, sulfinyl or sulfonyl), or two of R.sub.1 on adjacent carbon atoms represent alkylenedioxy;
• p is 1 or 2;
• R.sub.2 represents hydrogen or lower alkyl;
• one of R.sub.3 and R.sub.4 represents hydrogen and the other of R.sub.3 and R.sub.4 represents the group A-B in which A represents alkylene of 1 to 12 carbon atoms, alkynylene or alkenylene of 2 to 12 carbon atoms each, lower alkylene-phenylene, lower alkylene-(thio or oxy)-lower alkylene, lower alkylene-(thio or oxy)-phenylene, lower alkylenephenylene-lower (alkylene or alkenylene), or alkadienylene of 4 to 12 carbon atoms;
• and B represents carboxy, carboxy esterified as a pharmaceutically acceptable ester, carbamoyl, mono- or di-lower alkylcarbamoyl, cyano, hydroxycarbamoyl, or 5-tertrazolyl;
• a pyridyl-N-oxide thereof;
• or a pharmaceutically acceptable salt thereof;
• and wherein within the above definitions acylated hydroxy represents lower alkanoyloxy, benzoyloxy, benzoyloxy substituted on the phenyl ring by lower alkyl, halogen or lower alkoxy, or nicotinoyloxy;
• etherified hydroxy represents lower alkoxy, benzyloxy, benzyloxy substituted on the phenyl ring by lower alkyl, halogen or lower alkoxy, or pyridylmethoxy.