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US 4,536,493 AGranted
Saturated aminocyclitol derivatives, their preparation and medicaments containing these compounds
AssigneeBaker Aktiengesellschaft
InventorsBodo Junge, Lutz Muller
Life of this patent
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Abstract
The invention relates to saturated aminocyclitol derivatives, as defined herein in Formula (F). Also included in the invention are methods for preparing said saturated aminocyclitol derivatives, compositions containing said saturated aminocyclitol derivatives and methods for the use of said compounds and compositions to provide inhibition of .alpha.-glycoside hydrolases.
Claims15
A compound which is a saturated aminocyclitol derivative of the formula ##STR7## in which m and n independently of each other denote 0 or an integer from 1 to 8 and the sum of m+n has a value from 0 to 8,
- X represents OH, OR, SH, SR, NH.sub.2, NHR or NRR.sub.1, and
- R and R.sub.1 independently represent a straight chain or branched, saturated or unsaturated alkyl radical with 1 to 8 carbon atoms;
- a saturated or unsaturated carbocyclic radical with 3 to 6 carbon atoms;
- an aralkyl radical consisting of an alkylen- or -alkenylen-chain having 1 to 3 carbon atoms and an optionally substituted phenyl ring with one or two substituents selected from OH, NH.sub.2, Cl, CH.sub.3, NO.sub.2, COOH;
- an optionally substituted pheny ring with one or two substituents selected from -OH, -Cl, -CH.sub.3, -NO2, -COOH or ##STR8## together with the nitrogen atom to which they are bonded form a heterocyclic five- or six membered ring, selected from pyrrolidine, piperidine, piperazine, hexamethyleneimine, morpholine and N-methylpiperazine.
2 more elements
Dependencies are inferred from the claim text.