Heteropolysaccharide S-198
AssigneeMerck & Co., Inc.
InventorsJerry A. Peik, Suzanna M. Steenbergen, Harold R. Hayden
Life of this patent
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Abstract
A novel polysaccharide S-198 is disclosed composed of principally carbohydrate, 9-12% protein, and 2-4% O-acyl groups (calculated as O-acetyl). The carbohydrate portion comprises about 13-18% glucuronic acid and the neutral sugars mannose, glucose, and rhamnose in the approximate molar ratio 1:2:2. This polysaccharide is produced by a new Alcaligenes species ATCC 31853, in a suitable fermentation medium.
Claims3
The heteropolysaccharide S-198, which is principally carbohydrate, comprising 2-4% (calculated as O-acetyl) O-acyl groups, said O-acyl groups being primarily O-acetyl and O-succinyl and substantially free of O-formyl, 13-17.6% glucuronic acid, and the neutral sugars mannose, glucose, and rhamnose in the approximate molar ratio 1:2:2, wherein the ratio of terminally linked rhamnose to 1,4 linked rhamnose is 2:1 and the mannose is principally 1,4 linked.
Dependencies are inferred from the claim text.