Dental preparation, article and method for storage and delivery thereof

A combination of a collapsible tube article having flexible side walls and a composition consisting of a gel component and a paste component and contained in said article, said combination being suitable for use in combatting gum disease, said article comprising:

• (a) a first compartment containing said gel, said gel comprising (i) 1-10% by volume of hydrogen peroxide, (ii) 0.05-1.2% by volume of a water dispersible copolymer of acrylic acid cross-linked with polyallyl sucrose;
• (iii) 0.1-1.5% by volume of a non-ionic cellulose gum stabilizer (iv) purified water and (iv) a neutralizing agent selected from the group consisting of sodium hydroxide, potassium hydroxide, triethanolamine, diisopropylamine and ammonia in an amount sufficient to raise the pH of said gel to within about 3-6 such that the gel liquifies immediately upon contact with a mildly alkaline environment containing a strong electrolyte, thereby causing the release of bactericidally effective amounts of nascent oxygen;
• said gel having sufficient viscocity to support itself on the bristles of a toothbrush and sufficient fluidity to be dispensed from said flexible sidewall tube article upon squeezing;
• said first compartment having an orifice for dispensing controlled amounts of said gel upon squeezing of said flexible sidewalls;
• (b) a second compartment containing said paste, said paste comprising (i) 10-50% by weight of sodium bicarbonate;
• (ii) 1-6% by weight of a salt selected from the group consisting of NaCl and MgSO.sub.4 ;
• (iii) 1-3% by weight of a thickener-stabilizer selected from the group consisting of cellulose gum magnesium aluminum silicate, and mixtures thereof;
• (iv) 5-30% by weight of a humectant selected from the group consisting of glycerin, sorbitol, polyethylene glycol and polypropylene glycol, (v) purified water and (vi) 1-40% by weight of a cleansing-polishing agent selected from the group consisting of CaSO.sub.4, Ca.sub.3 (PO.sub.4).sub.2 and hydrated aluminum oxide, and (viii) 0.1-2.5% by weight of sodium lauryl sulfate;
• said paste having sufficient viscocity to support itself on the bristles of a toothbrush and sufficient fluidity to be dispensed from said flexible sidewall tube by squeezing, said second compartment having an orifice for dispensing controlled amounts of said paste upon squeezing of said flexible sidewalls substantially simultaneously with the dispensation of said gel in substantially equal amounts;
• said first compartment orifice and said second compartment orifice being adapted to dispense said gel and said paste respectively at the same use point, said first and second compartments having a common wall portion and said orifices being substantially adjacent;
• said article affording the following advantages over the use of an H.sub.2 O.sub.2, NaHCO.sub.3 and NaCl combination formed by dipping a toothbrush in a supply of H.sub.2 O.sub.2 followed by dipping said toothbrush in a paste consisting of NaHO.sub.3, NaCl and H.sub.2 O.sub.2 :
• (i) ready availability of premeasured bactericidally effective amounts of active H.sub.2 O.sub.2 and NaHCO.sub.3 sufficient to combat gum disease and effective against bacterial plaque;
• (ii) more vigorous release of said O.sub.2 due to the presence of said gel having a pH of about 3-6 on one hand and the presence of NaHCO.sub.3, which is alkanine, and NaCl, which is a strong electrolyte, on the other hand;
• (iii) improved penetration into gum tissues of nascent oxygen NaHCO.sub.3 and NaCl and more intimate contact with tooth and gum surfaces;
• and
• (iv) substantially smoother texture and a more palatable and pleasant taste.