Aqueous antimicrobial ophthalmic solutions
AssigneeAlcon Laboratories, Inc.
InventorRaymond L. Stark
Life of this patent
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Abstract
This invention relates to ophthalmic compositions which comprise quaternary ammonium salt having the formula ##STR1## wherein X=a pharmaceutically acceptable anion, such compositions providing aqueous disinfecting solutions for contact lenses as well as a preserved ocular compositions including contact lens treating solutions comfort drop solutions, preserved saline solutions, ointments and other ocular medicaments.
Claims25
An aqueous ophthalmic contact lens solution comprising:
- from about 0.00001 to about 3.0 percent by weight/volume of a quaternary ammonium compound having a number average molecular weight in the range of about 2,000 to about 30,000, said compound having the formula ##STR3## wherein X=a pharmaceutically acceptable anion;
- an effective amount of NaCl to provide isotonicity to said solution;
- and
- an effective amount of buffer to provide said solution with an ophthalmically acceptable pH.
An isotonic contact lens disinfecting solution comprising from about 0.001 to about 0.01 percent by weight/volume of a quaternary ammonium compound having a number average molecular weight in the range of about 2,000 to about 30,000, said quaternary ammonium compound having the formula ##STR4## wherein X=a pharmaceutically acceptable anion;
- an effective amount of NaCl to provide isotonicity to said solution;
- an effective amount of a buffer to provide said solution with an ophthalmically acceptable pH.
A method of imparting antimicrobial activity to an aqueous ophthalmic contact lens solution comprising:
- adding to said solution from about 0.00001% to about 3.0% by weight/volume of a quaternary ammonium salt as an antimicrobial agent having a molecular weight in the range of about 3,000 to about 14,000, said quaternary ammonium salt having the formula ##STR5## wherein X=a pharmaceutically acceptable anion.
Dependencies are inferred from the claim text.