US 4,522,742 A · Water soluble fluor compositions

Abstract

Water soluble fluors useful in enhancing images obtained in autoradiography have the general formula: [F].sub.x [B].sub.y [S].sub.z F is a moiety which acts as a fluor, e.g., a dehydro derivative of a compound which is a fluor; preferred examples include 4-(2,5-diphenyloxazolyl), 1-naphthylmethyl, 2-naphthyl, and 4-[5-(2-phenyloxazolyl)]phenyl. S is a surfactant moiety which makes the molecule hydrophilic, e.g., dehydro derivatives of surfactants; preferred examples include polyethylene glycol derivatives, sulfonic acids or salts thereof, aryl sulfonates, amines and quaternary ammonium compounds. B is a binding moiety which chemically binds the fluor moiety F with the surfactant S, and may be a chemical bond, or a disubstituted moiety such as an alkylene, e.g., methylene group. The variables x, y and z are integers which can generally vary from 1 to 10. A number of such compounds are disclosed, as well as methods of using such compounds, as well as compositions and products for fluorographic analysis in connection with chromatography, electrophoresis etc.

Claims5

Dependent claims

A composition of matter, comprising at least two water soluble fluors, each fluor having a structure in accordance with the formula:

[F].sub.x [B].sub.y [S].sub.z
wherein F is a component which absorbs energy and emits electromagnetic energy, S is a component which makes the fluor water soluble, and B is a chemical bond or other component which bonds a component F with a component S, and x,y and z are from 1 to 10, said composition comprising an aqueous solution of 4-[5-(2-phenyloxazolyl)]benzene sulfonic acid or a water soluble salt thereof and naphthalene-2-sulfonic acid or a water soluble salt thereof.

Dependencies are inferred from the claim text.

Water soluble fluor compositions

Life of this patent

Water soluble fluor compositions

Life of this patent

Abstract

Claims5