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OwnerHolger Kiesewetter, Heinz Myrenne +1inventors
InventorsHolger Kiesewetter, Heinz Myrenne, Hans-Gunther Roggenkamp
Estimating the term…
For measuring the deformation capacity of erythrocytes use is made of a sample vessel that is walled off into two spaces by a piece of foil with a pore therein. One such space is filled with buffer solution with erythrocytes and the other is filled with buffer solution without erythrocytes. A pressure head is produced acting across the foil for causing transit or passage of the erythrocytes through the opening, whose diameter is less than the major quiescent diameter of an erythrocyte so that information on the deformation capacity may be produced by measuring the transit time. This is done by electrodes placed on the two sides of the opening so that changes in the resistance to alternating current by an erythrocyte in transit may be sensed and the transit time taken. After about 200 transits the readings are processed in a processing unit.
In an apparatus for measuring the deformation capacity of erythrocytes comprising at least one sample vessel, a piece of foil walling said vessel off into two sample spaces, said foil having an opening therethrough for the motion of the liquid placed in the apparatus as a sample, said opening having a diameter smaller that the major quiescent diameter of an erythrocyte, means for producing a pressure head across the said foil in a buffer liquid placed in said vessel for causing a flow of said liquid through said opening, at least two electrodes placed on opposite or different sides of said foil, means for supplying said electrodes with voltage, and a voltage measuring system for measuring changes in said voltage at said electrodes on an erythrocyte making its way through said opening in a transit therethrough, wherein said measuring system times said transit.
Dependencies are inferred from the claim text.