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US 4,507,285 AGranted
Stabilized activated oxygen and pharmaceutical compositions containing said stabilized activated oxygen
OwnerFriedrich-Wilhelm Kuhneinventor
Life of this patent
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Abstract
The invention provides a stabilized activated oxygen in matrix of chlorite ions and pharmaceutical compositions containing this stabilized activated oxygen. The stabilized activated oxygen is present in the form of a solution. The medication can be used for the treatment of skin diseases or wound healing disorders.
Claims4
Stabilized activated oxygen which is enclosed in a matrix consisting of chlorite ions as represented by the general formula
- ClO.sub.2.sup.- .times.nO.sub.2 (activated)
- wherein n has the value 0.1-0.25, having an O.sub.2 band at 1562 cm.sup.-1 in the Raman spectrum and an O-O interval of 123 pm, obtained by reacting a chlorite in an aqueous solution with a hypochlorite in a molar ratio between chlorite and hypochlorite of 1:0.2 to 1:0.3, titrating the obtained alkaline solution with chloryl sulfuric acid to a pH value of 6.4-6.8 to form chlorine dioxide and a charge-transfer-complex (Cl.sub.2 O.sub.4).sup.-, expelling chlorine dioxide from this complex by addition of a peroxide selected from the group consisting of peroxide carbonates and peroxide borates, adding sodium peroxide, permitting the reaction mixture to stand for at least 4 weeks, and separating the resultant aqueous solution containing the complex of activated oxygen and chlorite ions from the carbonate or borate which precipitates from the reaction mixture.
Dependencies are inferred from the claim text.