Back to results
US 4,500,707 AGranted
Nucleosides useful in the preparation of polynucleotides
AssigneeUniversity Patents, Inc.
InventorsMarvin H. Caruthers, Mark D. Matteucci
Life of this patent
Estimating the term…
Abstract
New and useful intermediate nucleotides bound to an inorganic polymer support, including the preparation thereof, and processes for the conversion to oligonucleotides which are especially useful for the synthesis of polynucleotides, particularly ribonucleic (RNA) and deoxyribonucleic acids (DNA).
Claims16
A compound of the formula:
- ##STR12## wherein B is a nucleoside or deoxynucleoside base;
- R is H or a blocking group, A is H or OR;
- R' is a hydrocarbyl radical containing up to 10 carbon atoms and X is a amino group formed by removal of the hydrogen atom from a ring nitrogen of a nitrogen heterocyclic compound which contains unsaturation in the ring structure.
A compound of the formula:
- ##STR13## wherein B is a nucleoside or deoxynucleoside base;
- R is H or a blocking group;
- A is H or OR:
- R' is lower alkyl and X is a amino group formed by removal of the H atom of the amino nitrogen of a nitrogen heterocyclic compound.
1 more element
Dependencies are inferred from the claim text.