Apparatus for preparation of infusion grade water

A portable device for preparation of infusion grade water comprising:

• a chemical purification assembly including:
• an inlet port for receiving feed water,
• a first filter for filtration of gross particles and organic impurities, said filter having an input port connected to said inlet port, and an output port for discharging filtered water,
• means for reverse osmosis purification of said filtered water, said means having a retentate port for delivery of rejected water, said means generating permeate water, and wherein said means for reverse osmosis purification comprises membrane cartridges plumbed in parallel, connected to said first filter, each of said cartridges having a permeate port and a retentate port for delivering said water,
• means for deionization of said permeate water connected to said means for reverse osmosis purification, and,
• a second filter connected to said means for deionization, for fine particle filtration resulting in chemically pure water;
• an endotoxin filter receiving assembly including;
• an endotoxin filter having a means for receiving said chemically pure water, said endotoxin filter removing lipopolysaccharides of gram-negative bacteria from said chemically pure water and having a means for delivery of nonpyrogenic infusion grade water, and
• collection means integrally sealed with said endotoxin filter for receiving and storing free of contamination said infusion grade water, said collection means constructed and arranged for preparation of solutions for direct patient infusion;
• and,
• further including a recirculation system including a valve and conduit for delivering the retentate back to the means for reverse osmosis purification, said recirculation means including a needle valve in a rotameter for adjustment of the flow rate through each of the membrane cartridges.