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US 4,485,097 AGranted
Bone-equivalent and method for preparation thereof
AssigneeMassachusetts Institute of Technology
InventorEugene Bell
Life of this patent
Estimating the term…
Abstract
A bone-equivalent, useful in the fabrication of prostheses, is disclosed which is prepared from a hydrated collagen lattice contracted by fibroblast cells and containing demineralized bone powder.
Claims3
A bone-equivalent comprising a hydrated collagen lattice containing deminerlized bone powder and contracted with fibroblast cells.
A method of forming a bone-equivalent, comprising:
- a. combining a collagen solution with demineralized bone powder and fibroblast cells under conditions to form a gel mixture having demineralized bone powder and fibroblast cells dispersed within said gel mixture;
- b. maintaining the gel mixture prepared in step (a) under conditions which permit the contraction of said gel mixture to form a bone-equivalent.
Dependencies are inferred from the claim text.