Process for crosslinking polyamines
AssigneeThe Dow Chemical Company
InventorHarold H. Freedman
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Abstract
Polyalkylenepolyamines are crosslinked in a non-anhydrous environment to yield water-swellable, essentially water-insoluble gels. The polyalkylenepolyamine is contacted with a polyisocyanate at a pH between about 5 and about 8 and subjected to a high rate of agitation. The process of this invention can be employed to immobilize proteins, enzymes, antibodies, etc.
Claims12
A process for crosslinking a polyalkylenepolyamine wherein a polyisocyanate is contacted with an aqueous liquid comprising a polyalkylenepolyamine which is at a specific pH and which is subjected to a sufficiently high rate of agitation to yield a water-swellable, essentially water-insoluble gel.
A process for covalently immobilizing a protein wherein said protein is contacted with a polyalkylenepolyamine and a polyisocyanate in an aqueous liquid which is at a specific pH and which is subjected to a sufficiently high rate of agitation to yield a water-swellable, essentially water-insoluble gel.
Dependencies are inferred from the claim text.