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US 4,476,004 AGranted
Apparatus for electrofusion of biological particles
AssigneeD.E.P. Systems, Inc.
InventorHerbert A. Pohl
Life of this patent
Estimating the term…
Abstract
Apparatus and methods of use thereof are provided for fusing neutral polarizable biological bodies and sorting neutral polarizable biological bodies by imposing them to a non-uniform electric field. The dielectrophoretic effect of the non-uniform electric field will either impose variable displacements of the types of cells to facilitate sorting, or will align cells contiguously between a pair of electrodes in preparation for fusion. To fuse the cells the aligned cells are exposed to a direct current impulse.
Claims4
A device for fusing neutral polarizable bodies comprising
- at least two optically transparent elongated tubular members affixed to an optically transparent plate, said members colinearly aligned and spaced apart from each other;
- said members accommodating an optically transparent elongated tubular cell, said cell having exterior circumferential dimensions adapted for accommodation by the interior circumferential dimensions of said members, and said cell being of sufficient length such that each end thereof, respectively, extends partially into the openings of said respective members;
- two parallel electrodes longitudinally extending along the inner surface of said cell, said electrodes being electrically connected for switching to a direct current or alternating current power source.
Dependencies are inferred from the claim text.