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US 4,468,462 AGranted
Vectors for cloning in streptomyces
AssigneeEli Lilly and Company
InventorsNancy E. Malin, Jeffrey T. Fayerman, Michael D. Jones, James A. Mabe, Walter M. Nakatsukasa
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Abstract
The present invention discloses selectable recombinant DNA cloning vectors for use in Streptomyces.
Claims57
A recombinant DNA cloning vector comprising:
- (a) a functional origin of replication-containing restriction fragment of plasmid pNM100 and
- (b) one or more DNA segments that confer resistance to at least one antibiotic when transformed into a sensitive host cell, said host cell being susceptible to transformation, cell division, and culture.
Dependencies are inferred from the claim text.