Back to results
US 4,444,775 AGranted
Substituted imidazo[1,5-A]pyridines
AssigneeCiba-Geigy Corporation
InventorNeville Ford
Life of this patent
Estimating the term…
Abstract
Disclosed are e.g. novel 5-(carboxyalkyl)imidazo[1,5-a]pyridines, their derivatives and methods of synthesis. Said compounds are useful as selective thromboxane synthetase inhibitors for the treatment of diseases such as cerebral ischaemia, shock, thrombosis and ischaemic heart disease.
Claims16
A compound of the formula ##STR13## or a 5,6,7,8-tetrahydro derivative thereof, wherein R.sub.1 and R.sub.2 are hydrogen, halogen or lower alkyl;
- A is straight chain or branched alkylene of 1 to 12 carbon atoms, alkynylene, or alkenylene of 2 to 12 carbon atoms;
- B represents carboxy, lower alkoxycarbonyl, unsubstituted or mono- or di-(lower alkyl)carbamoyl, cyano or hydroxymethyl;
- or a pharmaceutically acceptable salt thereof.
Dependencies are inferred from the claim text.