Indane derivatives, pharmaceutical compositions thereof and method of preparation

A compound selected from the group consisting of a 1-piperazino-3-phenylindane of the formula:

• ##STR28## wherein R.sup.1 is selected from the group consisting of hydrogen, halogen, an alkyl group having one to four carbon atoms inclusive, an alkyloxy group having one to four carbon atoms inclusive, an alkylmercapto group having one to four carbon atoms inclusive, an amino group, an acetamino group, a cyano group, a trifluoromethyl group and an alkylsulfonyl group having one to four carbon atoms inclusive;
• R.sup.2 and R.sup.3 are each selected from hydrogen, halogen, alkyl and trifluoromethyl;
• and R.sup.4 is selected from an alkyl and alkenyl group, branched or unbranched, having one to six carbon atoms inclusive optionally substituted with one or two hydroxyl groups, a cyano group, an acetamino group, a cycloalkyl group having three to six carbon atoms in the ring, a phenyl group optionally substituted with a halogen atom, a hydroxy-substituted cyclohexyl group, a group ##STR29## wherein U is >O or >NH, and a group --(CH.sub.2).sub.n.CO.phenyl wherein "n" is an integer of one to four inclusive, and the phenyl group may be optionally substituted with a halogen atom, any hydroxy group present in the indane of Formula I being optionally esterified with an aliphatic carboxylic acid having two to twenty-four carbon atoms inclusive, at least one of both R.sup.1, R.sup.2 or R.sup.2, R.sup.3 always being other than hydrogen, and
• (2) a pharmaceutically-acceptable acid addition salt thereof.