Water and drug delivery system for suppository use
AssigneeMerck & Co., Inc.
InventorsRichard J. Harwood, Joseph V. Bondi
Life of this patent
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Abstract
A drug delivery system designed to deliver water and drug to the site of administration is composed of a core of an aqueous solubulizing system in a wax housing, which melts at body temperature, surrounded by a matrix of drug and water-dispersible excipients. The entire unit may also be coated with a semi-permeable membrane to modulate drug release.
Claims5
A drug delivery system comprising an aqueous core in a waxy housing, which housing melts at body temperature, surrounded by a matrix, shaped and sized for rectal or vaginal suppository use, comprising drug which is solubilized by the aqueous solution contained in the waxy core and water soluble or dispersible excipients.
Dependencies are inferred from the claim text.