Elastomeric active agent delivery system and method of use
AssigneeAlza Corporation
InventorHarold M. Leeper
Life of this patent
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Abstract
A transdermal therapeutic system is formed from a body member surrounding means at least a portion of which is an active agent loaded elastomer which is in a stretched condition during use. The tension created by the stretching of the elastomer is preferably from 20 to 35 psi and maintains the agent transferring contact between the skin and the transdermal therapeutic system. The transdermal therapeutic system may be in the form of a glove, sock, sleeve, cuff or band, for example.
Claims14
A transdermal therapeutic system for delivering active agent to the skin comprising body member surrounding means, at least a portion of said means being formed from an elastomeric matrix having active agent dispersed therethrough at a concentration greater than the saturation concentration of said agent in said elastomer, the skin proximal surface area of said matrix being smaller in its relaxed condition than in its condition of use when applied around a body member whereby the elastomeric matrix creates a compressive force on said body member sufficient to establish and maintain active agent transferring contact between said transdermal therapeutic system and the skin of said body member.
A method for delivering active agent to the skin which comprises applying around a body member an active agent delivery device, at least a portion of which is an elastomeric element, loaded with an active agent at a concentration above the saturation concentration of said agent in said elastomeric element and maintaining said elastomeric element in contact with the skin and in tension during the period of active agent delivery whereby the stress produced by said elastomeric element provides active agent transferring contact between the skin and the elastomeric element.
Dependencies are inferred from the claim text.