Process for fermentative production of amino acids
AssigneeKanegafuchi Chemical Industry Co., Ltd.
InventorsKan Hirakawa, Ryoji Takakuma, Koji Nomura, Masami Katoh, Kiyoshi Watanabe
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AssigneeKanegafuchi Chemical Industry Co., Ltd.
InventorsKan Hirakawa, Ryoji Takakuma, Koji Nomura, Masami Katoh, Kiyoshi Watanabe
Estimating the term…
A process is disclosed in which an amino acid-producing microorganism having an ability to assimilate lactic acid is aerobically cultivated in the presence of at least one lactic acid microorganism in an aqueous nutrient medium containing at least one carbohydrate which is assimilable by the lactic acid microorganism but nonassimilable or weakly assimilable by the amino acid-producing microorganism as the main carbon source and an accumulated amino acid is recovered from the culture broth. An industrially advantageous production of an amino acid has become feasible by utilizing inexpensive carbon sources or those organic substances in agricultural or livestock wastes that have heretofore not been effectively utilized.
In a process for producing an amino acid by mixed-cultivating microorganisms in an aqueous nutrient medium containing one or more carbohydrates, accumulating an amino acid in the resultant culture broth, and recovering the amino acid from the culture broth, the improvement comprising aerobically mixed-cultivating an amino acid-producing microorganism having an ability of assimilating lactic acid, but having no or a weak ability of assimilating at least one carbohydrate in the nutrient medium, and at least one lactic acid-producing microorganism having an ability of assimilating the carbohydrate which is nonassimilable or weakly assimilable by said amino acid-producing microorganism, whereby an amino acid is produced from the carbohydrate in one step operation.
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