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US 4,410,545 AGranted
Carbonate diester solutions of PGE-type compounds
AssigneeSyntex (U.S.A.) Inc.
InventorsCheng-Der Yu, Ursula Bruenner
Life of this patent
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Abstract
Stable compositions of PGE-type compounds are achieved by dissolving those compounds in carbonate diester solvents which may contain water up to the solubility limit of the carbonate diester.
Claims4
A stable pharmaceutical composition of a PGE-type compound having the following formula:
- ##STR4## wherein:
- R is hydrogen, a lower alkyl group of 1 to 4 carbon atoms, or the pharmaceutically acceptable, non-toxic salts of compounds in which R is hydrogen;
- and
- X is hydrogen, o-, m- or p-halo, o, m- or p-methyl or o-, m- or p-methoxy comprising a solution of said compound in propylene carbonate which may contain water in an amount up to the solubility limit of water for propylene carbonate.
1 more element
Dependencies are inferred from the claim text.