Process for producing antibiotic X-14868A
AssigneeAmerican Cyanamid Company
InventorsDavid P. Labeda, John H. E. J. Martin, Joseph J. Goodman
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Abstract
This invention relates to a novel process for the production of antibiotic X-14868A using the novel microorganism Antinomadura yumaense sp. nov.
Claims5
A process for preparing antibiotic X-14868A which comprises aerobically fermenting an antibiotic X-14868A-producing Actinomadura yumaense NRRL 125 15 or an antibiotic X-14868A-producing mutant thereof in a liquid medium containing assimilable sources of carbon, nitrogen, and inorganic salts, until substantial antibiotic activity is imparted to the fermentation broth and then recovering the antibiotic therefrom.
A process for preparing antibiotic X-14868A which comprises aerobically fermenting a liquid medium containing assimilable sources of carbon, nitrogen, and inorganic salts, which medium has been inoculated with a viable culture of an antibiotic X-14868A-producing Actinomadura yumaense NRRL 125 15 or an antibiotic X-14868A-producing mutant thereof, maintaining said fermentation culture at a temperature of 25.degree.-35.degree. C. for a period of 24-150 hours, harvesting the fermentation broth, and extracting the antibiotic therefrom.
A biologically pure culture of Actinomadura yumaense NRRL 125 15, said culture being capable of producing the antibiotic X-14868A in recoverable quantities upon fermentation in a liquid nutrient medium containing assimilable sources of carbon, nitrogen, and inorganic salts.
Dependencies are inferred from the claim text.