C-Terminal fragment of human chorionic gonadotropin
AssigneeToyo Jozo Kabushiki Kaisha
InventorsShigeo Katsuragi, Kaoru Morita, Sadami Kobari, Toshiharu Noda, Nobuaki Nakagawa, Susumu Watanabe
Life of this patent
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Abstract
A peptide of the formula R-SER-LEU-PRO-SER-PRO-SER-ARG-LEU-PRO-GLY-PRO-SER-ASP-THR-PRO-ILE-LEU-PRO-G LN-OH wherein R: H or R.sub.1 -Ser-Ser-Ser-Ser-Lys-Ala-Pro-Pro-Pro group, R.sub.1 : H or R.sub.2 -R.sub.3 -Asp-Asp-Pro-Arg-Phe-Gln-Asp group, R.sub.2 : H or R.sub.4 -Asp-His-Pro-Leu-Thr group, R.sub.4 : H-R.sub.5 -Gly-Gly-Pro-Lys group, R.sub.5 : Cys or Tyr group, and R.sub.3 : Cys or S-acetamidemethyl-Cys group, or salt thereof, has utility for the preparation of antibodies for assaying human chorionic gonadotropin or as a labelling reagent.
Claims1
A peptide of the formula
- R-SER-LEU-PRO-SER-PRO-SER-ARG-LEU-PRO-GLY-PRO-SER-ASP-THR-PRO-ILE-LEU-PRO-G LN-OH
- wherein
- R:
- H or R.sub.1 -Ser-Ser-Ser-Ser-Lys-Ala-Pro-Pro-Pro group,
- R.sub.1 :
- H or R.sub.2 -R.sub.3 -Asp-Asp-Pro-Arg-Phe-Gln-Asp group,
- R.sub.2 :
- H or R.sub.4 -Asp-His-Pro-Leu-Thr group,
- R.sub.4 :
- H-R.sub.5 -Gly-Gly-Pro-Lys group,
- R.sub.5 :
- Cys or Tyr group, and
- R.sub.3 :
- Cys or S-acetamidemethyl-Cys group,
- or pharmaceutically acceptable salt thereof.
Dependencies are inferred from the claim text.