# US 4,397,639 A · Device for the intermittent pulsatory application of fluid medicaments > Agents: this data is available as JSON from the patentgrep API and MCP server — see https://patentgrep.com/llms.txt - Number: US 4,397,639 A - Document ID: US4397639A - Status: Granted - Kind: A - Application number: 06/256,725 - Filed: 1981-04-23 - Granted: 1983-08-09 - Earliest claimed: 1980-04-24 - Assignees: Ferring Arzneimittel GmbH - Inventors: Wilhelm Eschweiler; Gerhard Leyendecker - Web page: https://patentgrep.com/patent/US4397639A ## CPC - A61M 5/142: Pressure infusion, e.g. using pumps - A61M 5/172: electrical or electronic - Y10S 128/12: Pressure infusion - A61M: DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY (introducing media into or onto the bodies of animals A61D7/00; means for inserting tampons A61F13/26; devices for administering food or medicines orally A61J; containers for collecting, storing or administering blood or medical fluids A61J1/05); DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY (surgery A61B; chemical aspects of surgical articles A61L); DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR {(Electrotherapy, e.g. producing anaesthesia by the use of alternating or intermittent currents A61N1/36021)} - Y10S: TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS ## Abstract A device for the intermittent pulsatory application of fluid medicaments, particular for the application of LH-RH for initiating ovulation in women having hypothalamic and hyperprolactinamic amenorrhea. Said device has a reservoir for the medicament and a hose connected to said reservoir for delivering said medicament to a patient, which reservoir and which hose are a prefabricated unit which can be inserted into the device and removed when the content of the reservoir is exhausted. Furthermore, said device has a roller-type pump acting onto said hose when it is stretched onto the needle-like rollers of said roller-type pump, and a D.C. motor for driving said pump and further control means for controlling said motor, said control means having a timer for pulse and pause times so that the motor is energized only for short periods not longer than several minutes while it is between each two of such running periods stopped for more than one hour. At least one battery is provided as energy source for the D.C. motor. ## Claims ### Claim 1 A portable apparatus adapted to be worn by a patient user for the intermittent pulsatory application of fluid medicament comprising: a disposable reservoir and hose assembly including a flexible reservoir container for medicament, a hose communicating between the reservoir container and a hose pumping portion having its discharge end in fluid communication with a catheter; a roller-type pump means including a a head portion rotatable about an axis of rotation and having angularly spaced rollers adapted to act on said hose pumping portion; a D.C. motor for driving said pump means; control means for controlling said motor including a timer for pulse and pause times; battery means for supplying electrical energy to said motor, and an openable housing and a frame cooperating to enclose and mount the pump means, motor, control means, battery means, and reservoir and hose assembly with said catheter extending from said housing for delivery of the medicament to a patient; said housing and frame cooperating to provide a recess for receiving said reservoir container and a pair of hose mounts for removably mounting said reservoir and hose assembly; a collar fixed to each end of said hose pumping portion; each of said collars being adapted to be resiliently biased into engagement with an associated one of said hose mounts with said hose pumping portion extended elastically through said hose mounts and tensioned against said rollers; said hose pumping portion, hose mounts and rollers being visible and directly accessible upon opening of said openable housing to enable insertion and removal of said reservoir and hose assembly without further disassembly of said apparatus. ### Claim 2 (depends on 1) An apparatus as set forth in claim 1, wherein said hose mounts comprise wall openings provided by said frame, said openings being sized to pass said hose pumping portion and to restrain said collars as they are resiliently biased into engagement with the adjacent wall portions. ### Claim 3 (depends on 1) An apparatus as set forth in claim 1, wherein said hose mounts comprise elongated wall slots adapted to receive said hose pumping portion and to interfere with said collars. ### Claim 4 (depends on 3) An apparatus as set forth in claim 3, wherein said frame includes a block element for mounting said pump means within said housing, said block element includes a wall adapted to extend between said head portion and said flexible reservoir container, and said elongated wall slots are provided in said wall. ### Claim 5 (depends on 1) An apparatus as set forth in claim 1, wherein said frame includes a block element, said pump means, motor, control means and battery means are mounted to said block element, said block element is fitted within a lower portion of said openable housing, and said block element is substantially coextensive with the interior region of said housing. ### Claim 6 (depends on 1) An apparatus as set forth in claim 1, wherein said hose pumping portion is adapted to extend in a single wrap around said head portion of said pump means, and said head portion includes a circumferentially extending guiding slot adapted to receive said hose pumping portion when the hose pumping portion is tensioned against said rollers. ### Claim 7 (depends on 6) An apparatus as set forth in claim 6 wherein said hose mounts are provided by said frame and comprise elongated slots extending through a wall of said frame, said slots are adapted to pass said hose pumping portion and to restrict said collars, said slots and said head portion of said pump means are located adjacent the top of said frame, and said housing includes a top cover which is removed when the housing is opened. ### Claim 8 (depends on 7) An apparatus as set forth in claim 7, wherein said guiding slot in said head portion has a depth which is greater than the diameter of said pumping portion. ### Claim 9 (depends on 7) An apparatus as set forth in claim 7, wherein said head portion includes a pair of axially spaced discs having said rollers axially extending therebetween, said discs and rollers cooperating to provide said guiding slot. ### Claim 10 (depends on 1) An apparatus as set forth in claim 1, wherein said hose pumping portion includes a silicone hose. ### Claim 11 (depends on 10) An apparatus as set forth in claim 10, wherein said silicone hose is an elastic protective sleeve. ### Claim 12 (depends on 1) An apparatus as set forth in claim 1, wherein said timer comprises a timing generator, a frequency divider and a driver stage which are connected in series. ### Claim 13 (depends on 1) An apparatus as set forth in claim 1, wherein a speed reducer means is provided between said motor and said roller-type pump means. ### Claim 14 (depends on 1) An apparatus as set forth in claim 1, wherein said control means operates to cause said motor to run not longer than several minutes while it is stopped between two running periods for more than one hour. ### Claim 15 (depends on 1) An apparatus as set forth in claim 1, further having a switch means for manually starting said motor when desired and a reset button for setting said control means to zero when said motor is started manually.