# US 4,395,257 A · Separating vessel and a separating centrifuge for use in the centrifugal separation of a liquid > Agents: this data is available as JSON from the patentgrep API and MCP server — see https://patentgrep.com/llms.txt - Number: US 4,395,257 A - Document ID: US4395257A - Status: Granted - Kind: A - Application number: 06/267,715 - Filed: 1981-05-28 - Granted: 1983-07-26 - Earliest claimed: 1980-06-10 - Assignees: Doltron AG - Inventors: Paul Manella - Web page: https://patentgrep.com/patent/US4395257A ## CPC - B04B 5/0442: {with means for adding or withdrawing liquid substances during the centrifugation, e.g. continuous centrifugation} - B04B 5/02: Centrifuges consisting of a plurality of separate bowls rotating round an axis situated between the bowls - B04B 5/0428: {with flexible receptacles} - B04B: CENTRIFUGES (high-speed drum mills B02C19/11; domestic spin driers D06F; analysing, measuring or monitoring physical or chemical properties of samples during centrifuging, see the relevant subclasses for these procedures, e.g. G01N) ## Abstract A separating vessel, intended to be inserted into a separating centrifuge, consists in a hollow cylinder manufactured from a soft PVC, whereby connection conduits for the feed of the liquid to be separated and for the discharge of the separated fractions open into said hollow cylinder. The separating centrifuge comprises a centrifuge rotor which is rotatable around a first axis of rotation and is driven by a driving motor via a driving arrangement. There is provided further a support mounted to the centrifuge rotor to rotate around a second axis of rotation. The two axis of rotation extend perpendicularly to each other. There is provided furthermore a connecting part receiving the connection conduits, which connecting part is mounted at one end against rotation and lies on the first axis of rotation. The supporting device rotates in order to equalize a twisting of the connecting conduits. The separating vessel is an integral part and accordingly it can be easily exchanged at a plasmapheresis in vivo whereby a remixing and contamination is not possible. ## Claims ### Claim 1 A separating vessel for use in a centrifugal separation of a liquid into fractions of different densities, comprising a double-walled hollow cylindrical body defining an annular chamber and comprising further at least three connection conduits opening into said annular chamber, which annular chamber is partitioned in longitudinal direction thereof such that one of said connection conduits opens into one longitudinal end section and the other of said connection conduits opens into the other, opposite end section of said annular chamber. ### Claim 2 (depends on 1) The separating vessel of claim 1 wherein said hollow cylindrical body consists in a hose welded together at its ends such that said annular chamber is partitioned, and wherein said connection conduits consist of individual hoses welded into said hollow cylindrical body. ### Claim 3 (depends on 1) The separating vessel of claim 1 wherein a plurality of lamella is provided within said annular chamber. ### Claim 4 (depends on 3) The separating vessel of claim 3 wherein said plurality of lamella is manufactured from an extruded medical soft PVC. ### Claim 5 (depends on 1) The separating vessel of claim 1 wherein it is manufactured from an extruded medical soft PVC. ### Claim 6 A separating centrifuge for the separation of a liquid into fractions of different densities, said centrifuge comprising a separating vessel and control means for controlling the separating process, said separating vessel consisting of a double-walled hollow cylindrical body defining an annular chamber and at least three conduits opening into and integral with said annular chamber, said control means including a centrifuge rotor rotatable about a first vertically extending axis of rotation, supporting means for supporting said separating vessel in said centrifuge rotor and arranged to rotate about a second horizontally extending axis of rotation, and a connection member for receiving connecting conduits of said separating vessel, said connecting conduits being held at one end against rotation and lying generally on said first axis of rotation and being mounted at the other end on said supporting means. ### Claim 7 (depends on 6) The separating centrifuge of claim 6 wherein there is provided a driving means for driving said centrifuge rotor and wherein said connection member is a flexible member intended for rotating said supporting means in order to neutralize the twisting of said connection conduits of said separating vessel due to the rotation of said centrifuge rotor and said separating vessel about said first axis. ### Claim 8 (depends on 6) The separating centrifuge of claim 6 together with first driving means for said centrifuge rotor and second driving means for said supporting means to neutralize the twisting of said connection conduits of said separating vessel due to the rotation of said centrifuge rotor and said separating vessel about said first axis. ### Claim 9 (depends on 8) The separating centrifuge of claim 8 wherein said separating vessel includes a double-walled hollow cylindrical body defining an annular chamber and said three connecting conduits opening into said annular chamber, said annular chamber being partitioned in longitudinal direction thereof such that one of said connecting conduits opens into one longitudinal end section and the other of said connecting conduits opens into the other, opposite end section of said annular chamber. ### Claim 10 (depends on 9) The separating centrifuge of claim 9 wherein said hollow cylindrical body consists of a tubing member welded together at its ends such that said annular chamber is partitioned, and wherein said connecting conduits are in the form of individual hoses welded into said hollow cylindrical body.