# US 4,394,378 A · 3-(Trimethoxysilyl) propyldidecylmethyl ammonium salts and method of inhibiting growth of microorganisms therewith

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- Number: US 4,394,378 A
- Document ID: US4394378A
- Status: Granted
- Kind: A
- Application number: 06/281,319
- Filed: 1981-07-08
- Granted: 1983-07-19
- Earliest claimed: 1981-07-08
- Inventors: Stewart E. Klein
- Web page: https://patentgrep.com/patent/US4394378A

## CPC

- A01N 55/00: Biocides, pest repellants or attractants, or plant growth regulators, containing organic compounds containing elements other than carbon, hydrogen, halogen, oxygen, nitrogen and sulfur (containing organo-phosphorus compounds A01N57/00)
- C07F 7/1804: {Compounds having Si-O-C linkages (Si-O-acyl linkages C07F7/1896)}
- A01N: PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF (preservation of food or foodstuff A23); BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES (preparations for medical, dental or toiletry purposes which kill or prevent the growth or proliferation of unwanted organisms A61K); PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- C07F: ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM (metal-containing porphyrins C07D487/22)

## Abstract

The growth of bacteria, fungi or the like is inhibited by contacting such microorganisms with an effective amount of certain silyl quaternary ammonium salts, e.g., 3-(trimethoxysilyl) propyldidecylmethyl ammonium chloride.

## Claims

### Claim 1

A silyl quaternary ammonium compound having the formula ##STR1## wherein X is selected from the group consisting of fluoride, chloride, bromide, iodide, sulfate and acetate.

### Claim 2

3-(trimethoxysilyl)propyldidecylmethyl ammonium chloride.

### Claim 3

A method of inhibiting the growth of Staph aureus and/or K. pneumoniae on surface reactive substrates by contacting said organisms with a silyl quaternary ammonium compound of the formula ##STR2## wherein X is selected from the group consisting of fluoride, chloride, bromide, iodide, sulfate and acetate, in an amount effective to inhibit the growth of said organisms.

### Claim 4 (depends on 3)

The method of claim 3, wherein the quaternary ammonium compound is 3-(trimethoxysilyl)propyldidecylmethyl ammonium chloride.

### Claim 5 (depends on 3)

The method of claim 3 wherein said substrate is a siliceous material.

### Claim 6 (depends on 3)

The method of claim 3 wherein said substrate is a metal.

### Claim 7 (depends on 3)

The method of claim 3 wherein said substrate is selected from the group consisting of leather, wood, rubber and plastic.

### Claim 8 (depends on 3)

The method of claim 3 wherein said substrate is made of natural or synthetic textile fibers.

### Claim 9 (depends on 8)

The method of claim 8 wherein the quaternary compound is employed in an amount of from 0.1 to 1.0% by weight of said textile substrate.