# US 4,393,214 A · Preparation of 2-chloro-5-trifluoromethylpyridine and 2-chloro-5-perchlorofluoromethylpyridines

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- Number: US 4,393,214 A
- Document ID: US4393214A
- Status: Granted
- Kind: A
- Application number: 06/243,428
- Filed: 1981-03-13
- Granted: 1983-07-12
- Earliest claimed: 1978-12-07
- Assignees: Imperial Chemical Industries PLC
- Inventors: Norman L. Roberts; Graham Whitaker
- Web page: https://patentgrep.com/patent/US4393214A

## CPC

- C07D 213/61: Halogen atoms or nitro radicals
- C07D: HETEROCYCLIC COMPOUNDS (macromolecular compounds C08)

## Abstract

2-chloro-5-trifluoromethylpyridine or a 2-chloro-5-perchlorofluoromethylpyridine is prepared by chlorination of 3-trifluoromethylpyridine or a 3-perchlorofluoromethylpyridine respectively in the vapor phase at a temperature in the range from 100.degree. C. to 500.degree. C.

## Claims

### Claim 1

A process for the preparation of 2,6-dichloro-3-trifluoromethylpyridine which consists essentially of vaporizing 3-trifluoromethylpyridine and chlorinating the vaporized 3-trifluoromethylpyridine by contacting the same in the vapour phase with gaseous chlorine at a temperature in the range from 400.degree. C. to 500.degree. C. using at least one mole of

### Claim 2 (depends on 1)

A process according to claim 1 wherein the proportion of chlorine

### Claim 3 (depends on 1)

A process according to claim 1 wherein the reaction mixture contains an

### Claim 4 (depends on 3)

A process according to claim 3 wherein the diluent is carbon tetrachloride.