# US 4,393,141 A · Method and device for examining urine for particulate constituents

> Agents: this data is available as JSON from the patentgrep API and MCP server — see https://patentgrep.com/llms.txt

- Number: US 4,393,141 A
- Document ID: US4393141A
- Status: Granted
- Kind: A
- Application number: 06/352,070
- Filed: 1982-02-25
- Granted: 1983-07-12
- Earliest claimed: 1981-03-04
- Assignees: Battelle-Institut e.V.
- Inventors: Gert Schlueter; Wilhelm Schuster
- Web page: https://patentgrep.com/patent/US4393141A

## CPC

- G01N 1/4077: {by other techniques involving separation of suspended solids}
- G01N 33/48: Biological material, e.g. blood, urine (G01N33/02, G01N33/26, G01N33/44, G01N33/46 take precedence); Haemocytometers (counting blood corpuscules distributed over a surface by scanning the surface G06M11/02)
- G01N 33/487: of liquid biological material
- Y10T 436/25375: Liberation or purification of sample or separation of material from a sample [e.g., filtering, centrifuging, etc.]
- Y10T 436/255: including use of a solid sorbent, semipermeable membrane, or liquid extraction
- G01N: INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES (measuring or testing apparatus or processes other than immunoassay, involving enzymes or microorganisms C12M, C12Q)
- Y10T: TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION

## Abstract

To examine urine for particulate constituents, the urine is pased through a filter of synthetic fibers that are soluble in alcohol or in an alcohol-water mixture immediately after withdrawal. The filter material together with the constituents retained in it is then immediately dissolved in a cell-fixing solvent, in which it is protected from environmental influences and stored until it is examined. An appropriate device for the implementation of this method consists of a urine collector and a filter cartridge which is fastened to the collector by a spring catch and can be detached after the urine has been passed through the filter, and connected liquid-tight with a storage vessel containing the solvent.

## Claims

### Claim 1

Method of examining urine for particulate constituents comprising:
(a) passing voided or withdrawn urine through a filter of synthetic fibers to capture said particulate constituents, said synthetic fibers being soluble in alcohol or in aqueous alcohol;
(b) contacting the synthetic fibers resulting from step (a) with alcohol or aqueous alcohol to simultaneously dissolve the synthetic fibers and to fix the particulate constituents whereby an examinable specimen is obtained; and
(c) storing the examinable specimen resulting from step (b) until the specimen is examined.

### Claim 2 (depends on 1)

The method of claim 1 wherein the particulate constituents are cells.

### Claim 3 (depends on 1)

Method as claimed in claim 1 wherein a cytopigment is added to the alcohol or aqueous alcohol.

### Claim 4

Device for carrying out the method of examining urine for particulate constituents, the device consists essentially of (a) a urine collector, and (b) a detachable filter cartridge, which is affixed to said collector, said filter cartridge containing, as filter material, synthetic fibers that are soluble in alcohol or in aqueous alcohol, after the urine has passed through the filter, and after the collector has been removed, a liquid-tight connection is establishable between one opening of the filter cartridge and a storage vessel and the other opening is closable in a liquid-tight manner.

### Claim 5 (depends on 4)

Device as claimed in claim 4 wherein the outlet of the filter cartridge is placed on the storage vessel and the inlet of the filter cartridge is sealed with the cover of the storage vessel.

### Claim 6 (depends on 5)

Device as claimed in claim 5 wherein the storage vessel is a beaded rim bottle and the filter cartridge is connected with the vessel by a spring catch.

### Claim 7 (depends on 4)

Device as claimed in claim 4 wherein the storage vessel is a beaded rim bottle and the filter cartridge is connected with the vessel by a spring catch.