# US 4,393,081 A · Methyl 3-acetamido-2-(5-methoxy-indol-3-yl) propanoate and hypotensive use thereof

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- Number: US 4,393,081 A
- Document ID: US4393081A
- Status: Granted
- Kind: A
- Application number: 06/315,638
- Filed: 1981-10-28
- Granted: 1983-07-12
- Earliest claimed: 1981-10-28
- Assignees: Miles Laboratories, Inc.
- Inventors: Robert N. Schut; Max E. Safdy; Enrique Hong
- Web page: https://patentgrep.com/patent/US4393081A

## CPC

- C07D 209/20: substituted additionally by nitrogen atoms, e.g. tryptophane
- A61P 9/12: Antihypertensives
- C07D: HETEROCYCLIC COMPOUNDS (macromolecular compounds C08)
- A61P: SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS

## Abstract

Disclosed is the novel compound methyl 3-acetamido-2-(5-methoxyindol-3-yl) propanoate which is useful as an anti-hypertensive agent.

## Claims

### Claim 1

Methyl 3-acetamido-2-(5-methoxyindol-3-yl) propanoate of the formula: ##STR3##

### Claim 2

A method of treating hypertension in a individual requiring such treatment which comprises administering to such individual an anti-hypertensively effective amount of a compound of the formula: ##STR4##