# US 4,393,078 A · Bupropion and ethanol

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- Number: US 4,393,078 A
- Document ID: US4393078A
- Status: Granted
- Kind: A
- Application number: 06/358,354
- Filed: 1982-03-15
- Granted: 1983-07-12
- Earliest claimed: 1982-03-15
- Assignees: Burroughs Wellcome Co.
- Inventors: Anthony W. Peck
- Web page: https://patentgrep.com/patent/US4393078A

## CPC

- A61K 31/135: having aromatic rings {, e.g. ketamine, nortriptyline (methadone A61K31/137)}
- A61K: PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES (devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms A61J3/00; chemical aspects of, or use of materials for deodorisation of air, for disinfection or sterilisation, or for bandages, dressings, absorbent pads or surgical articles A61L; soap compositions C11D)

## Abstract

This invention relates a method of restoring slowed mental ability in humans caused by ethanol by treatment with the compound of formula I ##STR1## or a pharmaceutically acceptable acid addition salt thereof in a non-toxic, effective therapeutic amount to a human in need thereof.

## Claims

### Claim 1

A method of reversing the impaired mental alertness effects of ethanol in a human, which comprises administering to a human who has consumed alcohol an effective, non-toxic amount of the compound of formula (I) ##STR3## or a pharmaceutically acceptable acid addition salt thereof to reverse the mental alertness effects of ethanol in the human.

### Claim 2 (depends on 1)

The method of claim 1 in which a pharmaceutically acceptable acid addition salt thereof is administered.

### Claim 3 (depends on 2)

The method of claim 2 in which the salt is the hydrochloride salt.

### Claim 4 (depends on 1, 2, 3)

The method of claim 1, 2 or 3 in which the compound or salt is administered in a pharmaceutically acceptable carrier therefor.

### Claim 5 (depends on 1, 2, 3, 4)

The method of claim 1, 2, 3 or 4 in which the compound or salt is administered orally.

### Claim 6 (depends on 5)

The method of claim 5 in which the compound or salt is administered in a pharmaceutically acceptable carrier therefor.

### Claim 7 (depends on 1)

The method of claim 1 in which the compound or salt is administered in a capsule or tablet containing a pharmaceutically acceptable carrier.

### Claim 8 (depends on 4)

The method of claim 4 in which the pharmaceutically acceptable acid addition salt is administered.

### Claim 9 (depends on 5)

The method of claim 5 in which the salt is hydrochloride.