# US 4,393,011 A · Method for the preparation of fluorine-containing phosphonates and phosphonic acids

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- Number: US 4,393,011 A
- Document ID: US4393011A
- Status: Granted
- Kind: A
- Application number: 06/355,481
- Filed: 1982-03-08
- Granted: 1983-07-12
- Earliest claimed: 1980-04-28
- Assignees: University of Iowa Research Foundation
- Inventors: Donald J. Burton; Richard M. Flynn
- Web page: https://patentgrep.com/patent/US4393011A

## CPC

- C07F 9/4037: {containing halogen or nitro(so) substituents}
- C07F 9/3856: {containing halogen or nitro(so) substituents}
- C07F: ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM (metal-containing porphyrins C07D487/22)

## Abstract

Fluorine-containing phosphonates and phosphonic acids are described. The method of preparation is a reaction of trialkylphosphites with dihalodifluoromethanes or a reaction of the salts of dialkylphosphites with halodifluoromethylphosphonates. The corresponding phosphonic acids are prepared by hydrolysis of the phosphonates.

## Claims

### Claim 1

A method of making a compound having the formula ##STR37## comprising reacting a compound of the formula: ##STR38## with a compound of the formula: ##STR39## wherein R and R' are alkyl from 1 to 6 carbon atoms, M is alkali metal and X is halogen selected from the group consisting of chlorine, bromine and iodine.