# US 4,391,995 A · 4-Phenoxy-phenoxy-alkane-carboxylic acid derivatives and process for their manufacture

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- Number: US 4,391,995 A
- Document ID: US4391995A
- Status: Granted
- Kind: A
- Application number: 06/265,902
- Filed: 1981-05-21
- Granted: 1983-07-05
- Earliest claimed: 1971-07-23
- Assignees: Hoechst Aktiengesellschaft
- Inventors: Helmut Nahm; Ernold Granzer
- Web page: https://patentgrep.com/patent/US4391995A

## CPC

- C07C 323/00: Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
- C07C 51/09: from carboxylic acid esters or lactones
- C07C 59/68: the oxygen atom of the ether group being bound to a non-condensed six-membered aromatic ring
- C07C: ACYCLIC OR CARBOCYCLIC COMPOUNDS

## Abstract

Novel 4-phenoxy-phenoxy-alkane-carboxylic acid derivatives of the formula I ##STR1## in which R.sub.1 stands for hydrogen, methylithio, cyclopentyl, cyclohexyl, phenyl, methylcycylohexyl, ethylcyclohexyl, or R.sub.1 and R.sub.3 together stand for a --CH.dbd.CH--CH.dbd.CH-- bridge or--unless at least one of the substituents R.sub.2 to R.sub.8 stands for hydrogen, or if R.sub.9 stands for a radical having at least 2 carbon atoms--for chlorine, R.sub.2 and R.sub.3, independent of one another, each stands for hydrogen, chlorine or alkyl of 1 to 4 carbon atoms, R.sub.4 stands for hydrogen, chlorine, alkyl of 1 to 4 carbon atoms, cyclopentyl, cyclohexyl, methylcyclohexyl or R.sub.3 and R.sub.4 together stand for a --CH.dbd.CH--CH.dbd.CH-- bridge, R.sub.5, R.sub.6 and R.sub.7, independent of one another, each stands for hydrogen or alkyl of 1 to 4 carbon atoms, R.sub.8 stands for hydrogen, alkyl of 1 to 4 carbon atoms or allyl, R.sub.9 stands for alkyl of 1 to 10 carbon atoms or phenyl and X stands for hydrogen, the cation of a physiologically acceptable inorganic or organic base of a hydrocarbon radical of 1 to 10 carbon atoms, having a strong action on the lipide and cholesterine metabolism and a process for this manufacture.

## Claims

### Claim 1

4-(2,4-dichlorophenoxy)-phenol and the alkali metal phenolates thereof.