Galenical compositions
AssigneeSandoz Ltd.
InventorThomas Cavanak
Life of this patent
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Abstract
The present invention provides a pharmaceutical composition comprising a pharmacologically active monocyclic peptide and a carrier comprising at least one of the following components: (a) a non-ionic ester of a triglyceride and a polyalkylene polyol, (b) a saturated fatty acid triglyceride, and (c) a mono- or di-glyceride having improved physical and absorption properties.
Claims15
A liquid pharmaceutical composition comprising a pharmaceutically effective amount of a cyclosporin and a carrier comprising the following components:
- (a) a trans-esterification product of a natural vegetable oil triglyceride and a polyalkylene polyol;
- (b) a vegetable oil;
- and
- (c) ethanol;
- whrein the ratio of component (a) to cyclosporin is 10:0.2 to 10 parts by weight;
- the amount of component (b) is 35 to 60% by weight based on the total weight of the composition, and the amount of component (c) is 1 to 20% by weight based on the total weight of the composition.
A liquid pharmaceutical composition comprising a pharmaceutically effective amount of a cyclosporin and a carrier comprising the following components:
- (a) a trans-esterification product of a hydrogenated vegetable oil triglyceride and a polyalkylene polyol;
- (b) a vegetable oil;
- and
- (c) ethanol;
- wherein the ratio of component (a) to cyclosporin is 10:0.2 to 10 parts by weight;
- the amount of component (b) is 35 to 60% by weight based on the total weight of the composition, and the amount of component (c) is 1 to 20% by weight based on the total weight of the composition.
Dependencies are inferred from the claim text.