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US 4,386,098 AGranted
6-Hydroxy-2-benzothiazolesulfonamide for the topical treatment of elevated intraocular pressure
AssigneeMerck & Co., Inc.
InventorsOtto Woltersdorf, Jr., Stuart R. Michelson, John M. Sondey, Harvey Schwam
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Abstract
6-Hydroxy-2-benzothiazolesulfonamide is useful for the topical treatment of elevated intraocular pressure. Ophthalmic compositions including drops and inserts are disclosed.
Claims7
A method for treating elevated intraocular pressure which comprises topically applying to an affected eye an intraocular pressure lowering effective amount of a carbonic anhydrase inhibitor of the formula:
- ##STR2## or an ophthalmologically acceptable salt thereof.
An ophthalmic insert for the topical treatment of glaucoma and ocular hypertension comprising an intraocular pressure lowering effective amount of a compound having the formula:
- ##STR3## including pharmaceutically acceptable salts thereof and an ophthalmologically acceptable solid water soluble polymer.
Dependencies are inferred from the claim text.