US 4,382,959 AGranted

Naphthalene derivatives, a process for their preparation and their use in anti-inflammatory pharmaceutical compositions

AssigneeBeecham Group Limited

InventorAlexander C. Goudie

Life of this patent

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Abstract

4-(6-Methoxy-2-naphthyl)-3-hydroxybutan-2-one and 4-(6-methoxy-2-naphthyl)buta-2,3-diol have good degrees of anti-inflammatory and analgesic activity coupled with an advantageous therapeutic ratio based on gastric irritancy and are non-oestrogenic. Their preparation and use are described.

Claims6

Dependent claims

A member selected from the group consisting of 4-(6-methoxy-2-naphthyl)-3-hydroxybutan-2-one and 4-(6-methoxy-2-naphthyl)buta-2,3-diol.

Dependencies are inferred from the claim text.

Facts

Application: 06/253,197Filed 13 Apr 1981 · continuation
Priority: GB 45815/7823 Nov 1978
Granted: 10 May 1983
Term ends: Not estimatedThe source records don’t support an estimate.

Classification7 codes

C07C 49/255
Unsaturated compounds containing keto groups bound to acyclic carbon atoms: containing ether groups, [IMAGE cpc-sch-C07C-0958.gif] groups,[IMAGE…
C07C 41/26
By reactions not forming ether-oxygen bonds: by introduction of hydroxy or O-metal groups
C07C 43/23
Having an ether-oxygen atom bound to a carbon atom of a six-membered aromatic ring: containing hydroxy or O-metal groups
C07C 45/27
Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds: by oxidation

Family

Serial94,101Parent of this continuation · filed 14 Nov 1979
US 4,382,959 AThis patent

From the US filing history. Foreign family members aren’t listed.

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