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US 4,382,923 AGranted
Tetrapeptide acylhydrazides, their production and use
AssigneeTakeda Chemical Industries, Ltd.
InventorsMasahiko Fujino, Mitsuhiro Wakimasu, Kiyohisa Kawai
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Abstract
Novel tetrapeptide acylhydrazides, inclusive of acid addition salts thereof, which have the formula: ##STR1## wherein R.sub.1 is hydrogen or methyl, R.sub.2 is lower alkyl; are useful as analgesics.
Claims12
A compound of the formula:
- ##STR5## wherein R.sub.1 is hydrogen or methyl, R.sub.2 is lower alkyl;
- or a pharmacologically acceptable acid addition salt thereof.
A pharmaceutical composition for pain-relieving in mammalian animals, which contains an effective amount of a compound of the formula:
- ##STR6## wherein R.sub.1 is hydrogen or methyl, R.sub.2 is lower alkyl;
- or a pharmacologically acceptable acid addition salt thereof, and a pharmacologically acceptable carrier.
Dependencies are inferred from the claim text.