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US 4,382,141 AGranted
Cis- and trans-4-(4-bromophenoxy)-1-[6-fluoro-1,2-benzisoxazole-3-yl)propyl]-3-ph enylpiperidines
AssigneeHoechst-Roussel Pharmaceuticals Inc.
InventorsSolomon S. Klioze, Frederick J. Ehrgott
Life of this patent
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Abstract
Novel 4-aryloxy- and 4-arylthio-3-phenylpiperidines and related compounds, physiologically acceptable salts thereof and intermediates therefor possessing analgesic, antidepressant properties, and a process for the preparation of such compounds, derivatives and intermediates are described.
Claims2
Trans- 4-(4-bromophenoxy)-1-[6-fluoro-1,2-benzisoxazole-3-yl)propyl]-3-phenylpiper idine, or a physiologically acceptable salt thereof.
Cis-4-(4-bromophenoxy)-1-[6-fluoro-1,2-benzisoxaz ole-3-yl)propyl]-3-phenylpiperidine, or a physiologically acceptable salt thereof.
Dependencies are inferred from the claim text.