Pretreatment of glucose feedstock
AssigneeUop LLC
InventorsRonald P. Rohrbach, Mary J. Maliarik
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Abstract
Commercial glucose solutions used as feedstock for enzymatic conversion of glucose to fructose by glucose isomerase often contain materials which act as poisons toward the enzyme. It has been found that these poisons can be removed, or destroyed, by treatment of the feedstock with oxidizing agents, chief of which is hydrogen peroxide.
Claims9
In a method of converting glucose to fructose using an immobilized glucose isomerase system, the improvement wherein a feedstock containing glucose and minor amounts of isomerase poisons, prior to contacting with the immobilized glucose isomerase system, is treated with an oxidizing agent selected from the group consisting of peroxides, hypohalites, perhalates, and persulfates at a pH from about 6 to about 9 at a temperature from about 10.degree. to about 80.degree. C. for a time and in an amount effective to increase the productivity of said immobilized glucose isomerase system above that productivity occurring when the enzymatic isomerization is carried out without the presence of said oxidizing agent, the treatment being for a time sufficient to destroy said poisons.
Dependencies are inferred from the claim text.