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US 4,381,775 AGranted
Method for low pressure filtration of plasma from blood
AssigneeTakeda Chemical Industries, Ltd.
InventorsYukihiko Nose', Paul S. Malchesky
Life of this patent
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Abstract
A method for carrying out separation of plasma from whole blood, in which whole blood is passed through a filtration membrane means of a material suitable for separating plasma from whole blood and having a pore size from 0.1 to 0.6 microns at positive pressure differential across the membrane in a range up to just below 50 mm Hg. This provides an increased flow as compared to the flow obtained with higher pressures.
Claims6
A method of separating plasma from whole blood, comprising the step of:
- directing a flow of whole blood across one face of a filtration membrane means which is made of a material suitable for separating plasma from whole blood and having a pore size from 0.1 to 0.6 microns, said flow being at a flow velocity of from 5 to 1500.sup.cm /min and being at a depth sufficient for separating plasma from the flow of blood, and at the same time generating a positive pressure differential across said membrane up to just below 50 mm Hg. for forcing plasma through the membrane, and collecting the plasma separated by the membrane.
Dependencies are inferred from the claim text.