Amino-alcohol derivatives
AssigneeKyowa Hakko Kogyo Co., Ltd.
InventorsHiroshi Takizawa, Yoshimasa Oiji, Kazuhiro Kubo
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Abstract
New amino-alcohol derivatives and processes for production thereof are disclosed. These compounds exhibit .alpha. and .beta.-adrenergic receptor blocking activity or they act to increase the flow of blood of certain organs.
Claims13
A compound of the formula ##STR116## wherein R.sub.1 represents ##STR117## and R.sub.4 represents ##STR118## wherein Me represents a methyl group, and the pharmaceutically acceptable acid addition salts thereof.
1-(3-methylphenoxy)-3-(1,4-benzodioxane-2-methaneamino)-2-propanol.
1-(4-acetamidophenoxy)-3-(1,4-benzodioxane-2-methaneamino)-2-propanol.
1-(2-cyanophenoxy)-3-(1,4-benzodioxane-2-methaneamino)-2-propanol.
1-(4-butyrylamido-2-acetyl)phenoxy-3-(1,4-benzodioxane-2-methaneam ino)-2-propanol.
1-(4-ethoxyca rbonylmethyl)phenoxy-3-(1,4-benzodioxane-2-methaneamino)-2-propanol.
1-(2,3-dimethylphenoxy)-3-(1,4-benzodioxane-2-methaneamino)-2-propanol.
1-(5-fluoro-3-methyl-2-benzofuranyl)-2-(1,4-benzodioxane-2-methaneamino ) ethanol.
1-(4-acetamidophenoxy)-3-(1,4-benzodioxane-6-methaneamino)-2-propanol.
1-{3,4-dihydro-1(2H)-naphthalenon-5-yl}oxy-3-(1,4-benzodioxane-6-methan eamino)-2-propanol.
1-(4-carbamoylm ethylphenoxy)-3-(1,4-benzodioxane-6-methaneamino)-2-propanol.
Dependencies are inferred from the claim text.