Pretreatment of glucose feedstock with reducing agents
AssigneeUop LLC
InventorsRonald P. Rohrbach, Mary J. Maliarik
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Abstract
Commercial glucose solutions used as feedstocks for enzymatic conversion of glucose to fructose by glucose isomerase often contain materials which act as poisons toward the enzyme. It has been found that these poisons can be removed, or destroyed, by treatment of the feedstock with reducing agents which are water soluble and water stable metal hydrides, such as sodium borohydride.
Claims8
In a method of converting glucose to fructose using an immobilized glucose isomerase system, the improvement wherein a feedstock containing glucose and minor amounts of isomerase poisons, prior to contacting with the immobilized glucose isomerase system, is treated with a water soluble and water stable metal hydride at a pH from about 7 to about 9 at a temperature from about 10.degree. to about 80.degree. C. for a time and in an amount effective to increase the productivity of said immobilized glucose isomerase system above that productivity occurring when the enzymatic isomerization is carried out without the presence of said metal hydride, the treatment being for a time sufficient to destroy said poisons.
Dependencies are inferred from the claim text.