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US 4,381,306 AGranted
Hydroxypropyl-triazole compounds, their production and their medicinal use
AssigneeBayer Aktiengesellschaft
InventorsErik Regel, Karl H. Buchel, Ingo Haller, Manfred Plempel
Life of this patent
Estimating the term…
Abstract
The invention relates to hydroxypropyl-triazole compounds and methods for their preparation. Also included are compositions containing said hydroxypropyl-triazoles and methods for the use of the said active compounds and compositions, as antimycotic agents.
Claims16
A hydroxypropyltriazole of the formula ##STR97## or a salt thereof, in which
- Az denotes a 1,2,4-triazol-1-yl or 1,3,4-triazol-1-yl radical,
- R denotes phenyl, naphthyl or tetrahydronaphthyl radical which is unsubstituted or substituted by halogen, C.sub.1 -C.sub.4 -alkyl, C.sub.1 -C.sub.4 -alkoxy or halogenoalkyl with 1 to 4 carbon atoms and up to 5 halogen atoms,
- R.sup.1 denotes a phenyl or C.sub.3 -C.sub.7 cycloalkyl radical which is unsubstituted or substituted by halogen or C.sub.1 -C.sub.4 -alkyl and
- R.sup.2 denotes a hydrogen atom, or
- R.sup.1 and R.sup.2 together, in the o-position relative to one another, represent an optionally halogen or C.sub.1 -C.sub.4 -alkyl substituted methylene bridge with 3 to 5 methylene groups, or, together with the phenyl ring, represent naphthyl,
- R.sup.3 represents halogen, an alkyl or alkoxy group with in each case 1 to 4 carbon atoms or halogenoalkyl with 1 to 4 carbon atoms and up to 5 halogen atoms and
- n is 0, 1, 2 or 3.
4 more elements
The compound of the formula ##STR98##
The compound of the formula ##STR99##
The compound of the formula ##STR100##
The compound of the formula ##STR101##
The compound of the formula ##STR102##
Dependencies are inferred from the claim text.